1·PurposeThe aim is to obtain recombinant hirudin gene using PCR method.
目的应用PCR方法获得水蛭素基因。
2·ConclusionThe experiments show that hirudin active factors have strong inhibition effect on S180 Tumor and CAM angiogenesis.
结论实验表明，水蛭素活性因子对S180肿瘤和CAM新生血管具有较强的抑制作用。
3·However, low production of natural hirudin, which was very expensive, limiting its use of in clinical practice.
但是天然水蛭素产量低，价格昂贵，限制了它在临床上的运用。
4·The anticoagulation effect of hirudin was better than dipyridamole (P
水蛭素抗凝作用明显强于潘生丁（P<0.01）。
5·Hirudin is an anticoagulant directly acting on thrombin. Its molecular biological and pharmacological properties, mechanism of action, current clinical researches and USES were reviewed.
水蛭素是特异的直接作用于凝血酶的抗凝剂。本文概述了其分子生物学特性、药理学特征、作用机理以及临床应用状况。