1·Objective. To assess the efficacy and safety of duloxetine in the treatment of chronic low back pain (CLBP).
目的：评估度洛西汀治疗慢性下腰痛的安全性和有效性。
2·The most common treatment-emergent adverse events in the duloxetine group included nausea, dry mouth, fatigue, diarrhea, hyperhidrosis, dizziness, and constipation.
度洛西汀组常见的突发不良反应包括恶心、口干、四肢乏力、腹泻、多汗、眩晕以及便秘。
3·Duloxetine appears to be less cardiotoxic and is licensed in the US and EU for alleiating DPN.
度洛西汀似乎心脏毒性较小，已在美国和欧洲获得使用许可用于治疗DPN。
4·Consider treatment with duloxetine, pregabalin, and gabapentin to improve quality of life in patients with neuropathic pain.
C考虑使用度洛西汀、普瑞巴林和加巴喷丁治疗以改善神经性疼痛患者的生活质量。
5·Conclusions: Duloxetine and Escitalopram are both effective and safe in the treatment of depression.
结论：度洛西汀和艾司西酞普兰对抑郁症患者同样安全有效。