1·During hepatocarcinogenesis induced by diethylnitrosamine (DENA) in rats, a period of decreased vitamin K-dependent carboxylase activity was observed followed by an increased period.
在二乙基亚硝胺(DENA)诱发大鼠肝癌过程中，维生素k依赖性羧化酶活性呈现先降低、后升高的现象。
2·Objective: to observe the inhibitory effects of se on diethylnitrosamine (DEN) induced hepatocarcinogenesis.
目的：观察硒对二乙基亚硝胺(DEN)诱发大鼠肝癌的影响。