1·Objective To optimize the synthesis technology of voriconazole.
目的优化伏立康唑的合成工艺。
2·The present drug2013drug interaction can be attributed to a strong inhibitory effect on cytochrome P450-3A4 activity by voriconazole.
究其原因，是因为伏立康唑对细胞色素P450-3A4活性有强大的抑制作用。
3·Voriconazole is the first-line antifungal agent for prevention of IFI.
伏立康唑是预防ifi的一线抗真菌制剂。
4·Based on the strength of the randomized study, the panel recommends voriconazole for primary treatment of these very uncommon manifestations of invasive aspergillosis (B-III).
在随机研究的力度的基础上，专家组推荐伏立康唑作为这些少见部位侵袭性曲菌病的用药首选。
5·Conclusions Voriconazole has a stronger antibacterial activity to Candida than Fluconazole, and is worthy of application in clinic for Candida infection.
结论伏立康唑比氟康唑对念珠菌有更高的抗菌活性，在抗念珠菌感染时具有较好临床应用价值。